Research Technician

Trudeau Institute

About the organization

Trudeau Institute hosts multi-disciplinary research devoted to translating the advances of basic science into new strategies to meet today’s urgent infectious disease challenges, collaborating with partners from academic and governmental biomedical laboratories, the biotech and pharmaceutical industries, and major global health focused foundations.

Duties

• Apply microbiology and molecular biology techniques to genetically engineer microbes for target deconvolution and recombinant protein expression.
• Express and purify recombinant proteins from various bacterial pathogens for in vitro biochemical assays to determine small molecule inhibitor efficacy.
• Mammalian and bacterial cell culture, and preparation of viral stocks using aseptic culture techniques, transformation, transduction, infection and viability assays.
• Record and analyze data, as well as write and present reports on research findings.
• After required training, conduct some studies in a biosafety level 3 (BSL3) environment.
• Assist in studies of antimicrobial efficacy in mouse models of mycobacterial disease.
• Preparation of growth media, solutions, and laboratory supplies.

Qualifications

• Bachelor’s degree (B.S.) in biological sciences or related discipline.

The successful candidate will have wet lab experience in microbiology, biochemistry, and/or molecular biology, which they will apply to develop and optimize biochemical assays of drug efficacy, as well as to construct genetically engineered mycobacterial strains with utility in mechanism of action determination and target identification. We seek a detail-oriented team member who enthusiastically engages in shared tasks and has a drive to advance their knowledge, with demonstrated skill in planning, prioritizing, and executing projects to meet commitments. Experience with preclinical animal models and cell culture is desirable.

Application instructions

Contact email: [email protected]

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